Cytokeratin 5 抗体 (AA 318-491)
Quick Overview for Cytokeratin 5 抗体 (AA 318-491) (ABIN6934855)
抗原
See all Cytokeratin 5 (KRT5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 318-491
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特异性
- This MAb recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium.Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express.Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5.
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交叉反应 （详细）
- Human.
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免疫原
- Recombinant human Cytokeratin 5 (KRT5) protein fragment (around aa 318-491) (exact sequence is proprietary)
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亚型
- IgG1 kappa
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anti-Keratin 5 (KRT5) antibody
KRT5 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2C2 unconjugated
anti-Keratin 5 (KRT5) (AA 316-590) antibodyKRT5 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 10C11E6 unconjugated
anti-Keratin 5 (KRT5) (AA 335-473) antibodyKRT5 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) antibodyKRT5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 316-590) antibodyKRT5 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal KRT5-3594 unconjugated
anti-Keratin 5 (KRT5) (AA 1-273) antibodyKRT5 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4A7 unconjugated
anti-Keratin 5 (KRT5) (AA 258-357) antibodyKRT5 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3D6D4 unconjugated
anti-Keratin 5 (KRT5) (AA 258-357) antibodyKRT5 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2C8E4 unconjugated
anti-Keratin 5 (KRT5) (AA 331-430) antibodyKRT5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 163-471) antibodyKRT5 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1:50-1:100 for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 or HeLa cells. Tonsil, Esophagus, Cervix or Urinary Bladder. Basal Cell or Squamous Cell Carcinoma.
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限制
- 仅限研究用
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缓冲液
- Tissue culture supernatant with 0.05% Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
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别名
- KRT5
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背景
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58 kDa Cytokeratin, CK5, Cytokeratin-5, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, KRT5, Type-II Cytoskeletal 5, Type-II keratin Kb5,Cytokeratin 5 (KRT5) (Basal, Myoepithelial & Mesothelial Cell Marker)
Cellular localisation: Cytoplasmic -
分子量
- 58kDa
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基因ID
- 3852, 433845
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UniProt
- P13647
抗原
-
